Gold Innovations Blog

Theranostics is a term which many of you may not be familiar with, but it describes much sought after combinations of  diagnostic and therapeutic processes. Traditionally, diagnostics and therapeutics are quite separate – if you are feeling unwell, you will visit your GP who will diagnose your illness (with a blood test, for example) and then prescribe the relevant treatment. Combining these two activities offers considerable benefits – speed of treatment, improved patient management/compliance and cost. Examples of theranostics currently on the market include Genentech’s Herceptin and Novartis’ Gleevec.

With this in mind I was fascinated to read this paper, recently published in the journal Nanotechnology. The team, working in the US and Europe, report the development of so-called ‘plasmonic nanobubbles’ (PNBs). These PNBs are effectively tunable and transient probes based around gold nanoparticles. The authors describe how such nanobubbles may potentially be used in 1) non-invasive imaging , 2) controlled-release, intra-cellular delivery and 3) selective and guided cell and tissue damage – true ‘theranostic’ potential!